Learn about Percocet (Oxycodone and Acetaminophen) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Oxycodone addiction is the largest part of America's opioid epidemic. Learn more about this painkiller, stats, and drug combinations. This is the list of Schedule II drugs as defined by the United States Controlled Substances Act. The following findings are required for drugs to be placed in this schedule: The drug or other substance has a high potential for abuse. Definition of Controlled Substance Schedules. Drugs and other substances that are considered controlled substances under the Controlled Substances Act (CSA) are divided into five schedules. U.S. DEPARTMENT OF JUSTICE • DRUG ENFORCEMENT ADMINISTRATION Diversion Control Division • 8701 Morrissette Drive • Springfield, VA 22152 • 1-800-882-9539 Percocet (oxycodone and acetaminophen) is a combination drug consisting of an opioid and a pain reliever and fever reducer (analgesic and antipyretic) used for the management of moderate to severe pain, usually for an extended time period. Schedule 2 (II) Drugs. The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. According to the DEA, drugs and other substances that are considered controlled substances under the CSA are divided into 5 schedules. An updated and complete list of the schedules is published annually in Title 21 Code of Federal Regulations (C.F.R.) §§ 1308.11 through 1308.15. Federal Register/Vol. 82, No. 13/Monday, January 23, 2017/Notices 7921 records examined at length. One of the commenters maintained that such The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated.